Finalyse, a novel pre-harvest hide wash, has been proven to significantly reduce Escherichia coli (E. coli) O157:H7 at an exposure time of five minutes.

A recent third-party validation study was conducted to determine the optimum exposure time and efficacy of bacteriophage against E. coli O157:H7 on cattle hides. Finalyse was proven efficacious with a reduction >1.8 Log CFU/g at an exposure time of five minutes, one hour and four hours.

Finalyse decreases levels of the E. coli O157:H7 pathogen before animals enter the beef packing plant. Finalyse provides greater versatility and flexibility in processing.  Packers can be confident that, regardless of whether cattle move directly through the holding pens and into the plant or wait for four hours, Finalyse is still working to reduce E. coli O157:H7  levels on the hide.  Finalyse’s efficacy and flexibility make it a key first step in a multi-hurdle food safety intervention program.

How Phage Technology Works

Finalyse contains a mixture of naturally occurring phages with a unique mode of action that specifically targets E. coli O157:H7 and other Shiga toxin-producing E. coli (STEC) pathogens in beef cattle.

The phage technology in Finalyse uses E. coli as host cells to rapidly replicate. This weakens the E. coli cell wall, which bursts and releases new phages to destroy additional bacteria. It is the phage attachment that compromises an E. coli cell within 5 minutes.

Novel Application System

Finalyse can be added to multiple pre-harvest, hide-on application points both inside and outside the plant. It is applied using our overhead spray system in the holding pens or lairage area spray system. Finalyse and the Finalyse Application System™ easily configure to current pre-harvest, hide-on spaces.

Tackling E. coli During Warmer Weather

Since E. coli levels historically rise in tandem with seasonal temperatures, now is the perfect time for food safety managers to take a fresh look at which products, practices and technologies are the right choices for their plants.

For more information about Finalyse and Passport Food Safety Solutions, call 515-334-8035, email or visit